Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ENC-101-hPTG
- Development stage
- Preclinical
- Lead developer
- Encellin
- Modality
- Cell Therapies
- Administration
- Implant, Subcutaneous
01
Overview
ENC-101-hPTG is an investigational encapsulated cell therapy being developed by Encellin for the treatment of severe refractory hypoparathyroidism. The therapy utilizes Encellin's proprietary Encapsulated Cell Replacement Therapy (ENCRT) platform, which consists of a nanoporous, immunoprotective, and pro-angiogenic membrane pouch. This pouch is loaded with primary human parathyroid gland (PTG) cells. Once implanted subcutaneously, the device is designed to protect the allogeneic parathyroid cells from host immune rejection and fibrosis while allowing the free exchange of nutrients, calcium, and parathyroid hormone (PTH). By restoring physiological PTH secretion, ENC-101-hPTG aims to regulate systemic calcium homeostasis without requiring lifelong immunosuppression or daily hormone injections.
- Other names
- ENC 10x xPTGENC10x xPTGENC-10x xPTG
02
Targets
CaSR (Extracellular calcium-sensing receptor)PTH1R (Parathyroid hormone/Parathyroid hormone-related peptide receptor type 1)
Beyond the preview
Go deeper on ENC-101-hPTG.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ENC-101-hPTG.