Drug intelligence / Profile preview

Enefluid

Development stage
Unknown
Lead developer
Otsuka Pharmaceutical Factory, Inc.
Modality
Peptides, Small Molecules
Administration
Intravenous, Parenteral
01

Overview

Enefluid is a peripheral parenteral nutrition (PPN) solution developed and marketed by **Otsuka Pharmaceutical Factory**. It is a combination product containing glucose, amino acids, electrolytes, and Vitamin B1 (thiamine). Enefluid is specifically designed to provide nutritional support to patients who cannot obtain sufficient nutrition orally or enterally. It is the first PPN solution in Japan to incorporate Vitamin B1, which is essential for carbohydrate metabolism and helps prevent complications such as Wernicke's encephalopathy and lactic acidosis that can occur when glucose is administered to thiamine-deficient patients. In clinical practice, it is also utilized for intradialytic parenteral nutrition (IDPN) to treat malnutrition in patients undergoing maintenance hemodialysis.

Brand names
Enefluid
Other names
ENEFLUID InjectionGlucose, Amino Acids, Electrolytes, and Vitamin B1 Injection
02

Targets

SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)SERPINA1 (Alpha-1-antitrypsin)PDH (Pyruvate dehydrogenase complex)

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