Drug intelligence / Profile preview

enhanced autologous PSMA-CAR T

Development stage
Phase 1
Lead developer
Shanghai ChangZheng Hospital
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

Enhanced autologous PSMA-CAR T is a Chimeric Antigen Receptor (CAR) T cell therapy that utilizes a patient's own (autologous) T cells, which are genetically engineered to express a CAR targeting Prostate-Specific Membrane Antigen (PSMA). This therapy is being developed by Shanghai Changzheng Hospital for the treatment of refractory castration-resistant prostate cancer.

Other names
Enhanced autologous PSMA chimeric antigen receptor T cellsCART-PSMA cellsEnhanced autologous PSMA-CAR T-Shanghai Changzheng Hospital
02

Targets

PSMA (Prostate-specific membrane antigen)

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