Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ENHANZE
- Development stage
- Phase 2
- Lead developer
- Halozyme
- Modality
- Therapeutic Enzymes → Recombinant Proteins and Enzymes
- Administration
- Subcutaneous
01
Overview
ENHANZE is a proprietary drug delivery technology developed by Halozyme Therapeutics. It is based on the recombinant human hyaluronidase PH20 enzyme (rHuPH20), which locally degrades hyaluronan (HA)—a major component of the extracellular matrix in subcutaneous tissue. By breaking down HA, ENHANZE temporarily increases tissue permeability and enables rapid, high-volume subcutaneous administration of co-administered drugs that would otherwise require intravenous infusion. This technology facilitates faster drug absorption and dispersion, reduces administration time for patients and healthcare providers, and can extend dosing intervals for certain therapies. ENHANZE has been used to enable subcutaneous formulations of several commercialized biologics across multiple therapeutic areas[1][4][6].
- Brand names
- ENHANZEEnhanze SC
- Other names
- recombinant human hyaluronidase PH20rHuPH20rHuPH-20rHuPH 20
Beyond the preview
Go deeper on ENHANZE.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ENHANZE.