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Ensure Plus Advance with HMB is a high-calorie, high-protein oral nutritional supplement developed by Abbott. It is formulated as a milkshake-style complete nutrition drink containing 20g of high-quality protein and 1.5g of calcium beta-hydroxy-beta-methylbutyrate (HMB) per bottle. HMB is a metabolite of the essential amino acid leucine that works to reduce muscle protein breakdown and support muscle synthesis. The supplement is designed for adults with or at risk of disease-related malnutrition, sarcopenia, and involuntary weight loss, and is particularly targeted at older adults and pre-frail elderly populations. It is frequently utilized in multimodal prehabilitation programs to optimize recovery for patients preparing for or recovering from major surgery or illness.
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