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The Enterovirus 71 inactivated vaccine, developed by Anhui Zhifei Longkema Biopharmaceutical, is an inactivated virus vaccine designed to prevent hand, foot, and mouth disease (HFMD) caused by Enterovirus 71 (EV71) in susceptible persons aged 6 months and older. The vaccine works through inactivated EV71 antigens that induce protective neutralizing antibodies against Enterovirus 71, thereby preventing EV71-associated HFMD. This vaccine is one of the EV71 inactivated vaccines licensed in China, which are the world's only EV71 vaccines approved by a national regulatory authority. The biological target is Enterovirus 71, a major causative agent of HFMD that can lead to severe neurological complications in children. The modality is an inactivated virus vaccine, meaning it contains killed viral particles that stimulate an immune response without causing disease.
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