enterovirus 71 vaccine (vero cell), inactivated

Enterovirus 71 vaccine (vero cell), inactivated is an inactivated, whole-virus vaccine produced using vero cells and inactivated with formalin. It is designed to induce protective immunity against enterovirus 71 (EV-A71), which is a major causative agent of hand, foot, and mouth disease (HFMD). The vaccine works primarily by stimulating production of neutralizing antibodies against the VP1 capsid protein of EV-A71, conferring immunity and preventing severe outcomes, especially in children under five. The product was developed and licensed mainly in China, with three primary manufacturers (Sinovac Biotech, Beijing Vigoo, and Chinese Academy of Medical Science) having received approval from the Chinese NMPA following large-scale phase III trials. Its efficacy in preventing EV-A71-associated HFMD and severe neurologic complications is very high (90–100%) among young children[1][3][5].

Brand names

Sinovac EV71 vaccineVigoo EV71 vaccine

Other names

inactivated enterovirus 71 vaccineinactivated EV71 vaccineenterovirus 71 inactivated vaccineenterovirus71 inactivated vaccineenterovirus-71 inactivated vaccineformalin-inactivated EV71 vaccine