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Enterovirus Type 71 Vaccine, Inactivated (Vero Cells)
- Development stage
- Unknown
- Lead developer
- Beijing Zhifei Lvzhu Biopharmaceutical
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
This is an inactivated whole-virion vaccine developed by Beijing Zhifei Lvzhu Biopharmaceutical, a subsidiary of Chongqing Zhifei Biological Products, for the prevention of hand, foot, and mouth disease (HFMD) caused by Enterovirus A71 (EV-A71). The vaccine is produced by propagating EV-A71 in Vero cell cultures and then inactivating the virus with formaldehyde. It is administered intramuscularly and is designed to stimulate the production of neutralizing antibodies against the EV-A71 virus, which is a major cause of severe HFMD and associated neurological complications in children. The vaccine has progressed through clinical trials, including Phase III studies, to evaluate its efficacy, safety, and immunogenicity in infants and young children.
- Other names
- Inactivated Enterovirus 71 Vaccine (Vero Cells)EV71 Vaccine (Zhifei Lvzhu)
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