Drug intelligence / Profile preview

Enterovirus Type 71 Vaccine (Human Diploid Cell)

Development stage
Unknown
Lead developer
Jiangsu Provincial Center for Disease Control and Prevention
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This is an inactivated Enterovirus 71 (EV71) vaccine developed to prevent hand, foot, and mouth disease (HFMD) in children. The vaccine contains the EV71 virus grown in human diploid cells, inactivated with formaldehyde, and adsorbed onto an aluminum hydroxide adjuvant. It is designed to elicit protective neutralizing antibodies against Enterovirus A71, which is a major cause of severe HFMD and associated neurological complications in young children. The vaccine is typically administered as a two-dose primary series to infants and children aged 6 months to 5 years. Clinical trials, including Phase 4 studies conducted by the Jiangsu Province Centers for Disease Control and Prevention, have evaluated its safety, immunogenicity, and compatibility when co-administered with other routine pediatric vaccines such as Hepatitis B and Group A meningococcal vaccines.

Other names
Enterovirus Type 71 Vaccine, inactivated ( Human Diploid Cell )EV71 vaccineEV-71 vaccineEV 71 vaccineinactivated EV71 vaccineEnterovirus 71 vaccineEnterovirus71 vaccineEnterovirus-71 vaccine

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