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Entonil Crema
- Development stage
- Unknown
- Lead developer
- Epitech
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Topical
01
Overview
Entonil Crema is a topically applied medical device developed by Epitech Group SpA, specifically formulated to soothe skin reactions caused by insect bites, jellyfish, and nettles. The product is an ALIAmide-based cream containing adelmidrol, bromelain, and clove essential oil. It works through the ALIA (Autacoid Local Injury Antagonism) mechanism, where adelmidrol modulates the activity of cutaneous mast cells and non-neuronal immune cells to reduce allergic-inflammatory skin responses. Bromelain, a proteolytic enzyme, is included to assist in the elimination of irritating substances. Classified as a Class C Medical Device under EU Regulation 2017/745, Entonil Crema is marketed primarily for pediatric populations and is commercially available in Italian pharmacies.
- Brand names
- Entonil CremaENTONIL
- Other names
- Entonil
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)
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