Drug intelligence / Profile preview

enxtra

Development stage
Unknown
Lead developer
OmniActive Health Technologies
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

enXtra is a proprietary, standardized extract of **Alpinia galanga** (often called Thai ginger), developed as a caffeine-free nootropic that supports mental energy, alertness, and focus[1][2][4][7]. Clinically studied in healthy adults, enXtra has demonstrated the ability to increase alertness, reaction speed, and accuracy while reducing error rates and fatigue for up to five hours post-dose[3][5]. Its main mechanisms of action include:\n- **Dopamine transporter inhibition**: Compounds in Alpinia galanga bind to dopamine transporter proteins, reducing dopamine reuptake and enhancing dopamine signaling, particularly in attention-related neural pathways[1][5].\n- **Catechol-O-methyltransferase (COMT) inhibition**: Phytochemicals in Alpinia galanga inhibit COMT, the enzyme that breaks down dopamine, further sustaining dopamine's effects[1].\n- **Acetylcholinesterase inhibition**: Alpinia galanga compounds decrease acetylcholinesterase activity, increasing acetylcholine levels and supporting learning, memory, and sustained attention[1][5].\nThe product is non-GMO, gluten-free, vegan, and certified kosher and halal[1][6][7]. enXtra has obtained self-affirmed GRAS status in the USA and is approved for sale in North America, Europe, and Asia[1][2][4][7]. It is produced using a gentle, solvent-free, water-based extraction designed to preserve the rhizome's bioactive profile[1][7]. enXtra has a strong safety profile, showing no significant adverse cardiovascular, sleep, or habituation effects during studies[1].

Brand names
enXtra
Other names
enXtraAlpinia galanga extractThai ginger extract
02

Targets

DAT (Dopamine plasma membrane transport protein)COMT (Catechol-O-methyltransferase)Acetylcholinesterase

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