Drug intelligence / Profile preview

EP-7327

Development stage
Preclinical
Lead developer
Cadrenal Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

**EP-7327** is an investigational *oral small molecule* drug that acts as a potent and selective inhibitor of **Factor XIa (F11)**, a serine protease involved in the intrinsic pathway of blood coagulation. EP-7327 is being developed for the prevention and treatment of major thrombotic conditions, with its primary indication focused on **thrombosis**. By selectively targeting Factor XIa, EP-7327 aims to reduce the risk of clot formation while minimizing bleeding, a known risk of many current anticoagulants. The drug is IND-ready for chronic antithrombotic indications and represents a promising new class of anticoagulants under research. EP-7327 was originally developed by **eXIthera Pharmaceuticals** and is now under development by **Cadrenal Therapeutics** following acquisition[1][3][9].

Other names
EP-7327EP7327EP 7327
02

Targets

Factor XIa

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