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EPI-SK17 is a proprietary topical small molecule therapy being developed by EpiPharm for the treatment of seborrheic keratosis (SK). It is designed as a first-in-class treatment that works by inducing selective apoptosis in the keratinocytes that make up SK lesions. This mechanism allows for the non-invasive clearance of the growths, offering a potential alternative to physical destruction methods such as cryotherapy, curettage, or laser therapy, which can be associated with pain, pigmentary changes, and scarring. As of early 2024, EPI-SK17 has completed a Phase 2a dose-ranging study and is preparing to enter Phase 2b clinical trials.
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