Drug intelligence / Profile preview

epidural anesthetic cocktail

Development stage
Unknown
Modality
Small Molecules
Administration
Epidural
01

Overview

The epidural anesthetic cocktail is a combination pharmaceutical product designed for epidural administration following endoscopic lumbar discectomy. It comprises triamcinolone (a corticosteroid), bupivacaine (a local anesthetic, referred to as Marcaine in the context), and morphine (an opioid analgesic). This combination aims to alleviate postoperative pain, reduce hospital stay duration, decrease the time to first analgesia, lower post-operative opioid consumption, improve functional outcomes, and facilitate a quicker return to work, while also minimizing postoperative complications. The cocktail is applied by soaking it into a gelfoam and placing it on the epidura.

Brand names
Marcaine
Other names
Epidural Anesthetic Cocktail
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)MOR (Mu opioid receptor)

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