Drug intelligence / Profile preview

Epimedium and Morinda officinalis Oral Liquid

Development stage
Unknown
Lead developer
Guangdong Imvin Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Epimedium and Morinda officinalis Oral Liquid is a traditional Chinese medicine (TCM) formulation developed and manufactured by Imvin Pharma (Guangzhou Wanzheng Pharmaceutical Co., Ltd.). The product is an oral liquid composed of extracts from two primary herbs: *Epimedium* (Herba Epimedii) and *Morinda officinalis* (Radix Morindae Officinalis). In the context of TCM theory, it is indicated for tonifying kidney yang and strengthening the musculoskeletal system. The formulation contains active compounds such as icariin (from Epimedium) and various iridoid glycosides and polysaccharides (from Morinda officinalis), which are associated with immune modulation, endocrine support, and bone health. It is marketed as an over-the-counter (OTC) medication in China for symptoms including impotence, premature ejaculation, and soreness or weakness in the lower back and knees.

Other names
羊藿巴戟口服液Yanghuo Baji Oral Liquid
02

Targets

Gut microbiota tryptophan–5-hydroxytryptophan–serotonin metabolic enzymes (Gut Trp–5-HTP–5-HT enzymes)CYP3A4 (Cytochrome P450 3A4)

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