Drug intelligence / Profile preview

Epionce

Development stage
Phase 4
Lead developer
Episciences
Modality
Small Molecules
Administration
Topical
01

Overview

Epionce is a professional-grade cosmeceutical skincare line developed by Episciences, Inc., and founded by dermatologist Dr. Carl Thornfeldt. The brand's therapeutic philosophy is based on the Barrier Repair and Anti-Inflammatory model of skin health, which posits that most skin aging and disease states result from a compromised stratum corneum and chronic sub-clinical inflammation. Epionce products are formulated with a proprietary blend of botanical ingredients—including meadowfoam, flax, apple, and date extracts—designed to penetrate the skin barrier to deliver essential lipids (cholesterol, ceramides, and free fatty acids) and inhibit pro-inflammatory mediators. Clinical studies have demonstrated its efficacy in improving conditions such as photoaging, acne vulgaris, atopic dermatitis, and psoriasis, often performing comparably to prescription-strength topicals like tretinoin or corticosteroids with fewer side effects.

Brand names
Epionce
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)

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