Drug intelligence / Profile preview

Epivac

Development stage
Phase 4
Lead developer
Suez Canal University
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Intradermal
01

Overview

Epivac is a commercial bee venom (apitoxin) preparation developed in Egypt for the treatment of inflammatory and autoimmune conditions, including recalcitrant localized plaque psoriasis. Administered via intradermal injection, Epivac contains a complex mixture of active peptides and enzymes, primarily melittin, apamin, adolapin, and phospholipase A2. These components exert anti-inflammatory, analgesic, and immunomodulatory effects. In clinical trials, Epivac has been shown to significantly reduce psoriasis severity (as measured by the Physician Global Assessment and Psoriasis Area and Severity Index) and decrease serum levels of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha).

Brand names
Epivac
Other names
bee venomapitoxin
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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