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EPK 004 is a preclinical-stage small molecule combination therapy under development by EPIK Biosciences. It is designed as a synergistic combination of ketamine- and/or dextromethorphan (DXM)-based compounds that target the N-methyl-D-aspartate (NMDA) receptor. The program is being developed for the treatment of various central nervous system and pain disorders, including depression, anxiety disorders, opioid use disorder, post-traumatic stress disorder (PTSD), and chronic and severe pain.
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