Drug intelligence / Profile preview

EPK 005

Development stage
Preclinical
Lead developer
EPIK Biosciences
Modality
Small Molecules
Administration
Intravenous, Sublingual, Topical
01

Overview

EPK 005 is a preclinical-stage small molecule combination therapy under development by EPIK Biosciences. Rooted in the company's proprietary platform focused on NMDA receptor modulation, EPK 005 is a ketamine- and/or dextromethorphan (DXM)-based synergistic combination designed to treat neuropsychiatric and pain disorders. The candidate is being investigated for the treatment of depression, anxiety disorders, opioid use disorder, post-traumatic stress disorder (PTSD), and chronic and severe pain. By combining NMDA receptor antagonists with other synergistic active ingredients, EPIK Biosciences aims to enhance therapeutic efficacy, durability, and safety while enabling potential at-home administration.

02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)

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