Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
EPON
- Development stage
- Unknown
- Lead developer
- Thrift Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
EPON is a brand of pharmaceutical products developed and marketed by Thrift Pharmaceuticals. It is available in multiple oral formulations, including tablets containing cyproheptadine, capsules combining cyproheptadine with dried yeast, and a syrup formulation containing cyproheptadine hydrochloride, tricholine citrate, and sorbitol. Cyproheptadine is a first-generation antihistamine with antiserotonergic and anticholinergic properties. It acts as an antagonist at histamine H1, serotonin (5-HT2A, 5-HT2B, 5-HT2C), and muscarinic acetylcholine receptors. By blocking H1 receptors, it alleviates allergic symptoms such as itching, swelling, and rhinitis. Its antiserotonergic activity on the appetite center of the hypothalamus stimulates appetite, making it useful for treating anorexia and promoting weight gain. Tricholine citrate acts as a lipotropic agent and bile acid-binding agent, helping to mobilize fat from the liver and support hepatic function. Sorbitol serves as an osmotic laxative to ease constipation and as a pharmaceutical vehicle. Dried yeast provides essential B-complex vitamins to support nutritional recovery.
- Brand names
- EPONEpon SyrupEpon Tablet
- Other names
- Cyproheptadine + Dried YeastCyproheptadine + Tricholine Citrate + SorbitolCyproheptadine, Dried Yeast, Tricholine Citrate, and Sorbitol
02
Targets
HTR2A (Serotonin receptor 5-HT2A)HTR2C (5-hydroxytryptamine 2C receptor)HRH1 (Histamine H1 Receptor)
Beyond the preview
Go deeper on EPON.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on EPON.