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Equisetum arvense, commonly known as field horsetail, is a perennial pteridophyte widely utilized in traditional medicine, cosmetics, and modern nutraceuticals. It is distinguished by its high concentration of silicic acid and a diverse profile of bioactive secondary metabolites, including flavonoids (such as isoquercitrin and kaempferol), hydroxycinnamic acids, and unique steroidal glycoalkaloids like equisarmine. The extract demonstrates significant antioxidant, anti-inflammatory, and antimicrobial properties. Clinically, it is employed in formulations for hair growth (e.g., Viviscal) and chronic pain management (e.g., Assonal PEA, where it acts synergistically with palmitoylethanolamide). Research indicates its potential in neuroprotection via glutaminase inhibition, wound healing through enhanced collagen synthesis, and even agricultural applications as a bio-based fungicide against pathogens like Gnomoniopsis smithogilvyi.
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