Drug intelligence / Profile preview

equisetum arvense

Development stage
Unknown
Lead developer
Lifescience Italia
Administration
Oral, Topical
01

Overview

Equisetum arvense, commonly known as field horsetail, is a perennial pteridophyte widely utilized in traditional medicine, cosmetics, and modern nutraceuticals. It is distinguished by its high concentration of silicic acid and a diverse profile of bioactive secondary metabolites, including flavonoids (such as isoquercitrin and kaempferol), hydroxycinnamic acids, and unique steroidal glycoalkaloids like equisarmine. The extract demonstrates significant antioxidant, anti-inflammatory, and antimicrobial properties. Clinically, it is employed in formulations for hair growth (e.g., Viviscal) and chronic pain management (e.g., Assonal PEA, where it acts synergistically with palmitoylethanolamide). Research indicates its potential in neuroprotection via glutaminase inhibition, wound healing through enhanced collagen synthesis, and even agricultural applications as a bio-based fungicide against pathogens like Gnomoniopsis smithogilvyi.

Brand names
Assonal PEAViviscalBIOCLEAN
Other names
horsetailfield horsetailcola de caballocommon horsetail
02

Targets

AcetylcholinesteraseTYR (Tyrosinase)GLS1 (Glutaminase 1)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

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