ER-4003

ER-4003 is a generic small-molecule formulation of **quetiapine fumarate extended-release**, developed by SigmaPharm Laboratories. It is designed as a generic alternative to the reference listed drug **Seroquel XR**. Quetiapine is an atypical antipsychotic with a complex pharmacological profile, acting primarily as an antagonist at dopamine D2 and serotonin 5-HT2A receptors, as well as a partial agonist at 5-HT1A receptors. Its active metabolite, norquetiapine, also functions as a norepinephrine reuptake inhibitor. The extended-release formulation (ER-4003) utilizes SigmaPharm's proprietary drug delivery technology to maintain therapeutic plasma levels over a 24-hour period, allowing for once-daily dosing. It is indicated for the treatment of schizophrenia, bipolar disorder (including manic and depressive episodes), and as an adjunctive treatment for major depressive disorder.

Other names

quetiapine fumarate extended-releasequetiapine fumarate ER