Drug intelligence / Profile preview

Er-Xian Tang

Development stage
Unknown
Lead developer
Shuguang Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

Er-Xian Tang is a traditional Chinese herbal formula developed in the mid-20th century in Zhejiang Province. It is designed to replenish both Kidney Yin and Yang, tonify Kidney Jing (essence), purge deficiency fire, and regulate the Chong and Ren channels according to Traditional Chinese Medicine (TCM) theory. The formula consists of six main herbs: Curculigo orchioides rhizome (Xian Mao), Epimedium herb (Yin Yang Huo), Morinda officinalis root (Ba Ji Tian), Angelica sinensis root (Dang Gui), Anemarrhena asphodeloides rhizome (Zhi Mu), and Phellodendron amurense bark (Huang Bai). It is primarily used for symptoms associated with menopause such as hot flashes, night sweats, irritability, insomnia, fatigue, irregular menstruation due to kidney Yin-Yang deficiency or disharmony between the Chong and Ren channels. The mechanism of action involves nourishing Yin while tonifying Yang of the Kidneys; clearing empty heat; regulating hormonal balance; strengthening bones/tendons; invigorating blood circulation[1][3][4][5][6].

Brand names
Er Xian Tang (as sold by various TCM suppliers)
Other names
二仙汤Two Immortals DecoctionCirculigo and Epimedium Combination
02

Targets

ER (Estrogen receptor)AR (Adrenergic receptors)

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