Drug intelligence / Profile preview

Eramax Vet

Development stage
Unknown
Lead developer
Navana Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Eramax Vet is a veterinary fixed-dose combination powder developed by Navana Pharmaceuticals for oral administration in poultry. It contains five active ingredients: erythromycin (a macrolide antibiotic), neomycin (an aminoglycoside antibiotic), sulfadimidine (a sulfonamide antibiotic), trimethoprim (a dihydrofolate reductase inhibitor), and bromhexine (a mucolytic agent). This combination is indicated for the treatment of various respiratory and enteric bacterial conditions in poultry, including chronic respiratory disease (CRD), complicated chronic respiratory disease (CCRD), bronchopneumonia, infectious coryza, colibacillosis, fowl cholera, salmonellosis, diarrhea, enteritis, and staphylococcal infections. Erythromycin and neomycin inhibit bacterial protein synthesis by binding to the 50S and 30S ribosomal subunits, respectively. Sulfadimidine and trimethoprim act synergistically to block bacterial folic acid synthesis, while bromhexine acts as a secretolytic expectorant to reduce mucus viscosity and facilitate clearance.

Brand names
Eramax Vet
Other names
Erythromycin + Neomycin + Sulfadimidine + Trimethoprim + BromhexineErythromycin Stearate + Neomycin Sulfate + Sulphadimidine + Trimethoprim + Bromhexine HydrochlorideErythromycin, Neomycin, Sulfadimidine, Trimethoprim & Bromhexine
02

Targets

Bacterial RibosomeBacterial 50S ribosomal subunitDHFR (Dihydrofolate reductase)DHPS (Dihydropteroate synthase)Gag (HIV-1 Gag polyprotein)

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