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Erchen Wan
- Development stage
- Unknown
- Lead developer
- Southern Medical University
- Modality
- Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Erchen Wan is a classic Traditional Chinese Medicine (TCM) formula used to dry dampness, resolve phlegm, regulate Qi, and harmonize the stomach. It is traditionally indicated for cough with copious sputum, chest and epigastric fullness, nausea, and vomiting caused by damp-phlegm accumulation. The formula typically consists of four core herbal ingredients: *Pinellia ternata* (Banxia), *Citrus reticulata* (Chenpi), *Poria cocos* (Fuling), and *Glycyrrhiza uralensis* (Gancao). In clinical trials, such as those sponsored by Southern Medical University, Erchen Wan is evaluated for its potential to modify constitution scores and prevent the transition from a healthy state to suboptimal health in individuals with unbalanced TCM constitutions.
- Brand names
- Erchen PillsUHerb Erchen PillsUHerb Erchen Wan
- Other names
- Er Chen WanErchen-wanTwo-Ingredient Pill
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)PPARA (Peroxisome proliferator-activated receptor alpha)HSP90AA1 (Heat shock protein HSP90-alpha)RELA (Nuclear Factor Kappa B Subunit p65)PIK3R1 (Phosphoinositide-3-kinase regulatory subunit 1)STAT3 (Signal Transducer and Activator of Transcription 3)PIK3CA (Phosphoinositide 3-kinase alpha)AMPK (Adenosine monophosphate–activated protein kinase)
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