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Eryfotona AK-NMSC (ISDIN)

Development stage: Unknown
Lead developer: ISDIN
Modality: Small Molecules, Recombinant Proteins and Enzymes, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration: Topical

Overview

Eryfotona AK-NMSC is a topical medical device designed for the prevention and adjunctive treatment of actinic keratosis (AK) and other forms of non-melanoma skin cancer (NMSC). Developed by ISDIN and distributed in the Nordic regions by Allderma, it combines high-spectrum UV protection (SPF 100+) with DNA Repairsomes. These Repairsomes contain photolyase, a DNA repair enzyme encapsulated in liposomes, which identifies and repairs cyclobutane pyrimidine dimers (DNA lesions) caused by UV radiation. By providing a physical barrier against further UV damage and actively repairing existing subclinical damage within the cancerization field, it reduces the risk of AK recurrence and progression.

Brand names: EryfotonaEryfotona AK-NMSCEryfotona SPF 100+Eryfotona Actinica
Other names: DNA Repairsomes

Targets

TP53 (Cellular Tumor Antigen p53 R175H)

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