erythromycin ethylsuccinate

Erythromycin ethylsuccinate is a macrolide antibiotic and a prodrug ester of erythromycin. It exerts its antibacterial effect by binding to the 50S ribosomal subunit of susceptible bacteria, specifically targeting the 23S ribosomal RNA, which inhibits RNA-dependent protein synthesis and prevents bacterial growth. It is indicated for a variety of infections, including respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases caused by organisms such as *Streptococcus pyogenes*, *Streptococcus pneumoniae*, *Mycoplasma pneumoniae*, and *Chlamydia trachomatis*. It is frequently utilized as an alternative treatment for patients with penicillin hypersensitivity. The ethylsuccinate ester is formulated to improve oral absorption and reduce the bitter taste associated with erythromycin base.

Brand names

E.E.S.EryPedErythrocin Ethylsuccinate

Other names

erythromycin ethylsuccinateerythromycin 2'-(ethyl succinate)erythromycin ethyl succinate