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erythropoietin chitosan gel
- Development stage
- Phase 4
- Lead developer
- Ain Shams University
- Modality
- Recombinant Proteins and Enzymes, Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
Erythropoietin chitosan gel is an investigational topical biologic formulation developed by researchers at Ain Shams University. It consists of erythropoietin (EPO) incorporated into a thermosensitive hydrogel scaffold composed of 5% chitosan and 20% β-glycerophosphate disodium salt. The formulation is designed for topical application in periodontal surgery, specifically as an adjunct to split-thickness apically positioned flap procedures. Erythropoietin acts as a cytoprotective and pro-angiogenic agent that promotes tissue repair, stimulates cell proliferation, and exerts anti-inflammatory effects, thereby enhancing wound healing and increasing the width of attached gingiva in patients with gingival recession.
- Other names
- EPO gelerythropoietin-loaded chitosan gel
02
Targets
Erythropoietin Receptor
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