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Escherichia coli Symbio DSM 17252
- Development stage
- Unknown
- Lead developer
- Symbiopharm
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
**Escherichia coli Symbio DSM 17252** is a nonpathogenic probiotic *Escherichia coli* preparation used as the active bacterial component of the oral medicinal product **Symbioflor 2**. The product contains a bacterial concentrate with viable *E. coli* and autolysed bacterial material and is marketed by SymbioPharm for treatment of irritable bowel syndrome in adults. Its intended activity is microbiome- and gut immune-system modulation rather than binding to a defined molecular drug target. European regulators concluded that Symbioflor 2 could remain authorised for irritable bowel syndrome but not for the broader indication of functional gastrointestinal disorders. ([symbiopharm.de](https://www.symbiopharm.de/en/products/symbioflor-2))
- Brand names
- Symbioflor 2Symbioflor2Symbioflor-2Symbioflor E. coli
- Other names
- E. coli SymbioEscherichia coli SymbioEscherichia coli Symbio DSM 17252
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