Drug intelligence / Profile preview

escitalopram + RT2CK17

Development stage
Phase 2
Lead developer
Laureate Institute for Brain Research
Modality
Small Molecules
Administration
Oral
01

Overview

Escitalopram + RT2CK17 appears to be a combination drug consisting of escitalopram and an agent designated as RT2CK17. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) used primarily for the treatment of major depressive disorder and generalized anxiety disorder. It works by selectively inhibiting the reuptake of serotonin in the central nervous system, thereby increasing serotonergic activity[6][7][8]. The mechanism of action for RT2CK17 is not established in available literature or databases as of June 2025; no information about its pharmacology or clinical use could be found. Therefore, this combination may represent an investigational product or a non-standard formulation.

Other names
escitalopramS-citalopram(S)-citalopramescitalopramumS(+)-citalopram
02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))HTR2A (Serotonin receptor 5-HT2A)HTR2C (5-hydroxytryptamine 2C receptor)DRD2 (Dopamine D2 Receptor)DAT (Dopamine plasma membrane transport protein)HRH1 (Histamine H1 Receptor)mAChR (Muscarinic acetylcholine receptors)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)KCNH2 (Voltage-gated potassium channel subfamily H member 2)ADRA1A (α1A)

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