Drug intelligence / Profile preview

Escitalopram oxalate oral solution

Development stage
Unknown
Lead developer
Allergan
Modality
Small Molecules
Administration
Oral
01

Overview

PC-0091 is an oral solution formulation of escitalopram oxalate, a potent selective serotonin reuptake inhibitor (SSRI) developed by Changtai Pharmaceutical (also known as PharmaMax Corp). It is indicated for the treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD). As the S-enantiomer of citalopram, escitalopram exhibits high selectivity for the serotonin transporter (SERT) and lacks significant affinity for various other receptors, which minimizes potential side effects. The oral solution formulation offers a flexible dosing option that is particularly beneficial for pediatric, geriatric, or dysphagic patients who have difficulty swallowing traditional tablets or require precise dose titration. PC-0091 received marketing approval from the China National Medical Products Administration (NMPA) in 2021.

Other names
Escitalopram oxalateS-citalopram oxalateEscitalopramum
02

Targets

SERT allosteric site (Serotonin transporter allosteric site)

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