Drug intelligence / Profile preview

ESIT12

Development stage
Preclinical
Lead developer
Fytexia
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

ESIT12 is a standardized dry extract of poplar-type propolis, characterized by a high concentration of polyphenols, specifically phenolic acids such as caffeic, coumaric, ferulic, and isoferulic acids, as well as various flavones and flavonols. Developed by B Natural, it is produced using a multi-dynamic extraction (M.E.D.) process to ensure a consistent and potent chemical profile. ESIT12 is primarily investigated for its immunomodulatory and antioxidant properties, with clinical focus on its ability to reduce the incidence, severity, and duration of upper respiratory tract infections (URTIs). It has also been the subject of nutrikinetic studies to evaluate the bioavailability and metabolic profile of its phenolic constituents in healthy individuals.

Other names
poplar-type propolis dry extractpropolis dry extract ESIT12

Beyond the preview

Go deeper on ESIT12.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on ESIT12.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call