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ESK440
- Development stage
- Preclinical
- Lead developer
- University of Michigan
01
Overview
ESK440: sourced facts only. name: "Given the potential roles of ALK and FAK in NB, we evaluated the efficacy of a novel compound ESK440, which is a dual ALK and FAK inhibitor." [DOI:10.1158/1538-7445.am2022-2018]; target: "Given the potential roles of ALK and FAK in NB, we evaluated the efficacy of a novel compound ESK440, which is a dual ALK and FAK inhibitor." [DOI:10.1158/1538-7445.am2022-2018]; target: "Given the potential roles of ALK and FAK in NB, we evaluated the efficacy of a novel compound ESK440, which is a dual ALK and FAK inhibitor." [DOI:10.1158/1538-7445.am2022-2018]; developer: "1University of Michigan, Ann Arbor, MI." [DOI:10.1158/1538-7445.am2022-2018]; stage: "Intriguingly, ESK440 studies in NB xenograft model (NB-1) resulted in tumor regression in treated animals." [DOI:10.1158/1538-7445.am2022-2018]
02
Targets
ALK (Anaplastic lymphoma kinase receptor tyrosine kinase)FAK (Focal adhesion kinase)
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