Drug intelligence / Profile preview

essential oils mouthwash

Development stage
Unknown
Lead developer
Universidad de Santiago de Compostela
Modality
Small Molecules
Administration
Topical
01

Overview

An essential oils-based antimicrobial mouthwash formulation evaluated by researchers at the University of Santiago de Compostela for the treatment and prevention of gingivitis. The formulation typically consists of a combination of phenolic compounds, including thymol, eucalyptol, menthol, and methyl salicylate. It exerts its therapeutic effect by penetrating the oral biofilm and disrupting the cell walls and membranes of plaque-causing bacteria, thereby reducing bacterial vitality and biomass. In clinical trials conducted by the University, the mouthwash demonstrated significant antiplaque efficacy comparable to the gold standard 0.2% chlorhexidine, making it a viable long-term alternative for oral hygiene and gingivitis management.

Other names
essential oils formulationEO mouthwash
02

Targets

Bacterial cytoplasmic membrane and cell envelope

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