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Essential Pro

Development stage
Unknown
Lead developer
iVascular
Modality
Inhalation Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems
Administration
Intracoronary, Intra-arterial
01

Overview

Essential Pro is a paclitaxel-eluting drug-coated balloon (DCB) catheter developed for the treatment of coronary artery disease, specifically for dilatation of stenosis or occlusions in coronary arteries or bypass grafts—including small vessels—and for treating in-stent restenosis (ISR). The device delivers paclitaxel at a concentration of 3 μg/mm² using a proprietary TransferTech nanotechnology that ensures an ultrathin, multilayered and homogeneous microcrystalline coating. This design allows rapid and uniform transfer of the antiproliferative agent paclitaxel to the vessel wall within 30–60 seconds, inhibiting neointimal hyperplasia and reducing restenosis rates. The device features improved pushability, trackability, visibility (with metallic radiopaque markers), and fast deflation times due to its advanced shaft design and hydrophilic Hydrax Plus coating. Clinical studies have demonstrated low target lesion revascularization rates and minimal adverse events in both small vessel disease and ISR populations[1][2][3][4][5].

Brand names
Essential Pro
Other names
essential proEssential Pro DCBEssential Pro drug-coated balloon
02

Targets

TUBB (Tubulin (alpha and beta subunits))

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