Drug intelligence / Profile preview

estradiol

Development stage
Approved
Lead developer
Allergan
Administration
Oral, Transdermal, Topical, Vaginal, Intramuscular
01

Overview

Estradiol is an estrogenic steroid hormone that is used to treat various conditions related to estrogen deficiency. It works by replacing or supplementing the body's natural estrogen, which helps relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It is also used to prevent osteoporosis after menopause, treat hypoestrogenism, and in some cases, treat certain types of breast cancer and advanced androgen-dependent prostate cancer. Estradiol is available in multiple formulations including oral tablets, transdermal patches, gels, sprays, vaginal creams, vaginal tablets, vaginal rings, and injections.

Brand names
EstraceClimaraAloraEstradermVivelleVivelle-DotMinivelleDivigelElestrinEstroGelEvamistEstringVagifemFemringMenostarEstradotImvexxyDottiLyllanaEsclimEstrasorbFemtrace
Other names
Oestradiol
02

Targets

GPER1 (G protein-coupled estrogen receptor 1)ESR2 (ERβ)ESR1 (ERα)

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