Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
estradiol + levonorgestrel (Bayer)
- Development stage
- Phase 2
- Lead developer
- Bayer
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Wellnara** is a continuous oral fixed-dose hormone replacement therapy containing estradiol 1 mg, supplied as estradiol hemihydrate, and levonorgestrel 0.04 mg per film-coated tablet. It is used to treat estrogen-deficiency symptoms in postmenopausal women; estradiol replaces declining endogenous estrogen activity, while the progestin levonorgestrel provides progestogenic opposition to estrogenic stimulation of the endometrium in women with a uterus. Bayer has also conducted post-marketing surveillance of Wellnara in Japan in postmenopausal osteoporosis. ([gelbe-liste.de](https://www.gelbe-liste.de/produkte/Wellnara-1-mg-0-04-mg-Filmtabletten_501079/fachinformation))
- Brand names
- Wellnara
- Other names
- E2/LNG oralestradiol + levonorgestrelestradiol hemihydrate + levonorgestrelestradiol/levonorgestrel
02
Targets
ESR1 (ERα)ESR2 (ERβ)GPER1 (G protein-coupled estrogen receptor 1)PR (Progesterone receptor)
Beyond the preview
Go deeper on estradiol + levonorgestrel (Bayer).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on estradiol + levonorgestrel (Bayer).