estriol tripropionate

Estriol tripropionate is a semisynthetic steroidal estrogen and an ester derivative of estriol. It is marketed under the brand name Estriel and used as an estrogen medication. As an estrogen ester, it acts primarily as a prodrug for estriol, which exerts its effects by agonizing the estrogen receptor (ER). Estriol itself is considered a weak estrogen compared to other endogenous estrogens like estradiol. The primary clinical use of estriol esters such as estriol tripropionate has been in menopausal hormone therapy to treat symptoms like hot flashes and vaginal dryness. The drug is administered via intramuscular injection[5][3]. Its mechanism involves binding to nuclear estrogen receptors to modulate gene transcription and mediate typical estrogenic effects in target tissues[2][1].

Brand names

Estriel

Other names

oestriol tripropionateestriol tripropanoate