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Estromineral Serena Plus is an oral dietary supplement formulated to alleviate menopausal symptoms, support bone health, and maintain intestinal flora balance. Its ingredients combine **soy isoflavones** (phytoestrogens acting as weak estrogen receptor agonists), **Lactobacillus sporogenes** (Bacillus coagulans) as a probiotic supporting isoflavone activation and gut health, **chaste tree (Vitex agnus-castus) extract** (noted as a dopamine agonist and partial binder to estrogen receptors), **Magnolia officinalis extract** (modulates GABA-A receptor activity and cortisol), and minerals **calcium** and **magnesium** plus **vitamin D3** for bone support and neuromuscular regulation. Its primary indication is the relief of menopausal symptoms (hot flashes, insomnia, mood complaints, etc.) and improvement of well-being in post-menopausal women[1][3][4][6][8].
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