Drug intelligence / Profile preview

Estyme Lift

Development stage
Unknown
Lead developer
Symatese
Modality
Device-based Delivery → Drug Delivery Systems
Administration
Intradermal, Subcutaneous
01

Overview

Estyme Lift is a cross-linked hyaluronic acid (HA) dermal filler containing lidocaine, developed for facial aesthetic procedures. It is designed to add volume to tissue, restore skin contours, and correct moderate to severe nasolabial folds by injection into the dermis or hypodermis. The product utilizes proprietary C-HA.PURE TECHNOLOGY™, a cold temperature cross-linking process that preserves the natural structure of HA while requiring less BDDE (a common cross-linker), aiming for improved safety and efficacy. Clinical trials have demonstrated its non-inferiority and even statistical superiority over established HA-lidocaine fillers in improving wrinkle severity scores at 3 and 6 months post-injection. Estyme Lift is CE marked under EU Medical Device Regulation as a Class IV medical device, with ANVISA authorization in Brazil, and is marketed as Evolysse Lift in the United States[2][5][6][7].

Brand names
Estyme Lift
Other names
Evolysse Lift
02

Targets

NaV (Voltage-gated sodium channels)

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