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esubaglutide
- Development stage
- Preclinical
- Lead developer
- Innogen Pharma
- Modality
- Peptides
- Administration
- Subcutaneous
01
Overview
Esubaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist being investigated for the treatment of type 2 diabetes mellitus (T2DM), obesity, and obstructive sleep apnea (OSA). It is notably featured in clinical research conducted by Shanghai General Hospital, where researchers utilize millimeter-wave radar sleep monitoring to guide individualized dosing. This approach aims to optimize therapeutic outcomes by monitoring the apnea-hypopnea index (AHI) and predicting early efficacy in patients with comorbid obesity and moderate-to-severe OSA. As a member of the "-glutide" class, esubaglutide likely functions by mimicking the action of endogenous GLP-1, thereby improving glycemic control and promoting weight loss.
- Other names
- esubaglutide
02
Targets
GLP1R (GLP-1R)FcγR (Low affinity immunoglobulin gamma Fc region receptor II-c)FCGRT (Neonatal crystallizable fragment receptor)
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