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Drug intelligence / Profile preview
ethanol
- Development stage
- Approved
- Lead developer
- Eton Pharmaceuticals
- Modality
- Small Molecules
- Administration
- oral, intravenous, topical, inhalation
01
Overview
Ethanol is a small molecule organic compound with the formula C2H5OH. It is a clear, colorless, volatile liquid with a characteristic odor and burning taste. Ethanol acts as a central nervous system depressant by enhancing the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors and inhibiting excitatory neurotransmission via NMDA-type glutamate receptors. It is widely used as an ingredient in alcoholic beverages, as an industrial solvent, in pharmaceuticals (as an excipient or antiseptic), and as a biofuel additive to gasoline. Ethanol can be produced by fermentation of sugars using yeast or by chemical synthesis from ethylene[1][5]. In medicine, it is used topically as an antiseptic and disinfectant.
- Brand names
- Denatured AlcoholNozinNozin POPswabLavacolAlcare PlusInstant Hand Sanitizer
- Other names
- ethyl alcoholalcoholgrain alcoholabsolute alcohol
02
Targets
GABRR (GABA-A receptor subunit rho)NMDAR (Glutamate receptor ionotropic, NMDA)GABRA2 (Gamma-aminobutyric acid receptor subunit alpha 2)
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