ethinyl estradiol + cyproterone

Ethinyl estradiol + cyproterone is a fixed-dose combination oral medication containing two active ingredients: ethinyl estradiol, a synthetic estrogen, and cyproterone acetate, a synthetic progestogen with anti-androgenic properties. This combination is primarily used to treat women of reproductive age with moderate to severe acne related to androgen sensitivity or hirsutism (excessive hair growth), especially when other treatments have failed. Cyproterone acetate acts as an androgen receptor antagonist and suppresses ovarian androgen production, while ethinyl estradiol provides estrogenic activity that helps regulate the menstrual cycle and further reduces circulating androgens by increasing sex hormone-binding globulin. The combination also has contraceptive effects but should not be used solely for birth control due to an increased risk of thromboembolism compared to some other oral contraceptives[1][3][4][7].

Brand names

Diane-35Diane35Diane 35Gestra-35Gestra35Gestra 35BellgynBENAKLIN

Other names

co-cyprindiol