ethinyl estradiol + ethynodiol diacetate

**Ethinyl estradiol + ethynodiol diacetate** is a combination oral contraceptive containing two hormones: ethinyl estradiol (a synthetic estrogen) and ethynodiol diacetate (a synthetic progestin)[1][5][6]. It is used primarily for the **prevention of pregnancy** in women who choose oral contraceptives[1][2][6]. This combination prevents ovulation by suppressing the secretion of gonadotropins (FSH and LH); additionally, it alters cervical mucus to hinder sperm passage and changes the endometrial lining to reduce the likelihood of implantation[1][5][6]. It is formulated as monophasic oral tablets, usually with 21 hormone-containing and 7 inert tablets per cycle[5][8]. No contraceptive method is 100% effective and this medication does not protect against STIs[6]. Rarely, it may be used for management of hormonally related conditions (e.g., acne) when contraception is also desired[7]. The drug contains active ingredients known by their chemical names: ethinyl estradiol (19-nor-17\u03b1-pregna-1,3,5(10)-trien-20-yne-3,17-diol) and ethynodiol diacetate (19-nor-17\u03b1-pregn-4-en-20-yne-3\u03b2,17-diol diacetate)[1][2].

Brand names

Demulen 1/35Demulen 1/50Kelnor 1/35Kelnor 1/50Kelnor 1/35-28Zovia 1/35Zovia 1/35EZovia 1/50EValtya 1/35Valtya 1/50

Other names

ethynodiol diacetate and ethinyl estradiolEthynodiol/Ethinyl Estradiol