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Drug intelligence / Profile preview
ethyl salicylate
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Ethyl salicylate is a small molecule analgesic and anti-inflammatory agent belonging to the salicylate class. It is the ethyl ester of salicylic acid and is primarily used topically for the relief of musculoskeletal pain and inflammation, including sports-related pain. Its mechanism of action involves inhibition of cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) enzymes, leading to reduced prostaglandin synthesis and thus decreased pain and inflammation. Additionally, it acts as a counter-irritant by promoting local vasodilation when applied to the skin. Ethyl salicylate is also used in perfumery and artificial flavors due to its pleasant wintergreen-like odor.
- Other names
- ethyl 2-hydroxybenzoateethyl2-hydroxybenzoateethyl-2-hydroxybenzoateethyl o-hydroxybenzoatesalicylic acid ethyl estersalicylic ethersalicylic ethyl ester
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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