Drug intelligence / Profile preview

etomidate + fentanyl + lidocaine

Development stage
Unknown
Lead developer
Janssen Pharmaceutica
Modality
Small Molecules
Administration
Intravenous, Intrathecal
01

Overview

A combination of three medications used for procedural sedation and analgesia. Etomidate is a non-barbiturate hypnotic that acts at the GABA receptor level to produce anesthesia without significant cardiovascular depression[3][6]. Fentanyl is a fast-acting synthetic opioid that provides analgesia and helps reduce hypertensive and tachycardic responses to stimulation during procedures[4]. Lidocaine is a local anesthetic that can be used to enhance pain control.

02

Targets

MOR (Mu opioid receptor)NaV (Voltage-gated sodium channels)

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