Drug intelligence / Profile preview

eurycoma longifolia extract

Development stage
Unknown
Lead developer
Biotropics Malaysia
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Eurycoma longifolia extract, commonly known as Tongkat Ali or Longjack, is a botanical extract derived from the roots of the Eurycoma longifolia tree native to Southeast Asia. It is widely used as a dietary supplement and nutraceutical for its aphrodisiac, pro-fertility, and ergogenic properties. Standardized extracts, such as Physta and LJ100, have been co-developed by the Malaysian Government and the Massachusetts Institute of Technology (MIT) and are commercialized by Biotropics Malaysia. The extract is primarily investigated and used for male sexual health, late-onset hypogonadism, and male infertility, where it is believed to support endogenous testosterone production and improve sperm parameters.

Brand names
LJ100LJ-100LJ 100Physta
Other names
Eurycoma longifolia Jack extractEurycoma longifolia root extractLongjackMalaysian ginsengTongkat Ali
02

Targets

CYP19A1 (Aromatase)

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