Drug intelligence / Profile preview

EV101

Development stage
Preclinical
Lead developer
EV Therapeutics
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
01

Overview

**EV101** is a preclinical cancer immunotherapy candidate from **EV Therapeutics** built on the company's modified tumor extracellular vesicle platform. It is described as a first-in-class **extracellular vesicle based therapy** derived from modified tumor extracellular vesicles and has shown preclinical activity in solid tumor and advanced metastatic animal models, both as monotherapy and in combination with immune checkpoint inhibitors. Publicly available information indicates development focus in oncology, particularly advanced-stage colorectal cancer, but the precise molecular payload, formulation details, and definitive human dosing route have not been publicly disclosed.

Other names
EV-101EV101EV 101
02

Targets

PVRL4 (Nectin cell adhesion molecule 4)TUBB (Tubulin (alpha and beta subunits))

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