Drug intelligence / Profile preview

EV403

Development stage
Preclinical
Lead developer
EV Therapeutics
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
01

Overview

EV403 is an investigational, preclinical-stage therapeutic candidate being developed by EV Therapeutics for the treatment of hepatic cancer. It utilizes the company's proprietary extracellular vesicle (EV) platform, which engineers exosomes to serve as targeted delivery vehicles for therapeutic payloads. By leveraging the natural biocompatibility and cell-targeting capabilities of EVs, EV403 is designed to deliver its payload directly to liver cancer cells, potentially improving therapeutic efficacy while reducing systemic side effects. It is part of a broader pipeline of EV-based therapies focused on gastrointestinal and hepatic malignancies.

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