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EVD-005 is an engineered cytokine currently in the discovery stage, developed by Evozyne for the treatment of autoimmune diseases. The drug is part of a platform that utilizes protein engineering to create cytokines with 'biased' signaling properties, specifically designed to separate beneficial anti-inflammatory activity from unwanted pro-inflammatory effects. By modifying the protein's interaction with its receptor complex, Evozyne aims to develop a more targeted and safer therapeutic for immune-mediated conditions. As of early 2024, the specific cytokine target has not been publicly disclosed.
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